Henoch-Schönlein purpura causes
|
Henoch-Schönlein purpura Microchapters |
|
Differentiating Henoch-Schönlein purpura from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Henoch-Schönlein purpura causes On the Web |
|
American Roentgen Ray Society Images of Henoch-Schönlein purpura causes |
|
Risk calculators and risk factors for Henoch-Schönlein purpura causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
- The exact cause of HSP is not clear.
- It may be an abnormal immune system response to infection or an extreme allergic reaction. Other people may be genetically predisposed to developing HSP.
- In HSP, the antibodies are directed against the blood vessels causing vasculitis, leading to the leakage, and a subsequent rash.
- Allergic reaction: An extreme allergic reaction to certain foods may cause HSP.
Genetics: Although rare, HSP occurs in people within the same family, including in twins. This suggests that some cases of HSP may have a genetic cause, although there is no research to prove this. Other associations: Certain drugs, bacteria, insect bites, viral infections, food, cold weather, and trauma may also cause HSP.
The exact cause of HSP is not known. The body's immune system is believed to play a role in targeting the blood vessels involved. An abnormal immune response to an infection may be a factor in many cases. Approximately two-thirds of the cases of HSP occur days after symptoms of an upper respiratory tract infection develop.
Some cases of HSP have been linked to vaccinations for typhoid, cholera, yellow fever, measles, or hepatitis B; foods, drugs, chemicals, and insect bites. Some experts also say that HSP is associated with the colder weather of fall and winter.
In Henoch-Schonlein purpura, some of the body's small blood vessels become inflamed, which can cause bleeding in the skin, abdomen and kidneys. Why this initial inflammation develops isn't clear. It may be the result of the immune system responding inappropriately to certain triggers.
Nearly half the people who have Henoch-Schonlein purpura developed the disease after an upper respiratory infection, such as a cold. Infectious triggers may include chickenpox, strep throat, measles and hepatitis. Other triggers may include certain medications, food, insect bites or exposure to cold weather
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Cytarabine , Deferiprone, Ethacrynic Acid, Oxytetracycline |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
|
|
|
|