Restless legs syndrome epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Epidemiology and Demographics
Incidence
In community-based epidemiological surveys, RLS (Restless Leg Syndrome) has been studied as:
- A symptom only
- In this kind of symptoms ,prevalence estimates in the general adult population ranged from 9400 to 1500 per 100,000 individuals worldwide.
- A set of symptoms meeting minimal diagnostic criteria of the IRLSSG
- In this kind of symptoms ,prevalence estimates in the general adult population ranged from 3900 to 1400 per 100,000 individuals worldwide.
- When frequency/severity is added, prevalence ranged from 2.2% to 7.9% and when differential diagnosis is applied prevalence estimates are between 1.9% and 4.6%. In all instances, RLS prevalence is higher in women than in men.
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
.
- . In all instances, RLS prevalence is higher in women than in men. It also increases with age in European and North American countries but not in Asian countries. Symptoms of anxiety and depression have been consistently associated with RLS. Overall, individuals with RLS have a poorer health than non-RLS but evidence for specific disease associations is mixed. Future epidemiological studies should focus on systematically adding frequency and severity in the definition of the syndrome in order to minimize the inclusion of cases mimicking RLS.
Overview
Many doctors express the view that the incidence of restless leg syndrome is exaggerated by manufacturers of drugs used to treat it.[1] Other physicians consider it a real entity that has specific diagnostic criteria. [2]
Prevalence
The prevalence of paranoid personality disorder is 2,000 to 7,200 per 100,000 (2% to 7.2%) of the overall population.[3]
Epidemiology and Demographics
Often sufferers think they are the only ones to be afflicted by this peculiar condition and are relieved when they find out that many others also suffer from it. The severity and frequency of the disorder vary tremendously. Many people only experience symptoms when they try to sleep, while others experience symptoms during the day. It is common to have symptoms on long car rides or during any long period of inactivity (like watching television or a movie, attending a musical or theatrical performance, etc.) Approximately 80-90% of people with RLS also have PLMD, Periodic Limb Movement Disorder, which causes slow "jerks" or flexions of the affected body part. These occur during sleep (PLMS = Periodic Limb Movement while Sleeping) or while awake (PLMW - Periodic Limb Movement while Waking).
Developed Countries
Restless legs syndrome affects an estimated 2.7% of the general population in the U.S.A.[4]
Developing Countries
About 10 percent of adults in North America and Europe may experience RLS symptoms, according to the National Sleep Foundation, which reports that "lower prevalence has been found in India, Japan and Singapore," indicating that ethnic factors, including diet, may play a role in the prevalence of this syndrome.[5]
- ↑ Woloshin S, Schwartz L (2006). "Giving legs to restless legs: a case study of how the media helps make people sick". PLoS Med. 3 (4): e170. PMID 16597175.
- ↑ Montplaisir J; Boucher S; Nicolas A; Lesperance P; Gosselin A; Rompré P; Lavigne G (1998). Movement disorders. 13 (2): 324–9. PMID 9539348 http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&cmd=retrieve&dopt=AbstractPlus&list_uids=9539348. Missing or empty
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(help) - ↑ Diagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.
- ↑ Allen R, Walters A, Montplaisir J, Hening W, Myers A, Bell T, Ferini-Strambi L (2005). "Restless legs syndrome prevalence and impact: REST general population study". Arch. Intern. Med. 165 (11): 1286–92. PMID 15956009.
- ↑ "Welcome - National Sleep Foundation". Retrieved 2007-07-23.