Sjögren's syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

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Other diagnostic studies

• Tests which could help to diagnosis of Sjögren's syndrome include:
  • Schirmer test
    • A folded test strip of sterile filter paper is placed on the margin of each lower eyelid at the junction of the middle and lateral thirds. Ask the patient to close eyes gently for five minutes then the extent of wetting is measured. Wetting of less than 5 mm is demonstrative of tear deficiency and it is a classification criteria for Sjögren’s syndrome.
  • Ocular surface staining
    • It may be assessed to evaluate the damage to conjunctival and corneal epithelial cells with vital dyes such as rose Bengal dye, fluorescein and lissamine green dyes.