Restless legs syndrome natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of restless leg syndrome usually develop in the elderly patients, and start with symptoms such as Urge to move the legs and Uncomfortable and bothersome sensations in the affected limbs.[1][2]
- Complication of untreated restless leg syndrome are more prominent among children:
- If left untreated, children with restless leg syndrome may progress to develop cardiovascular problems, cognitive deficits, attention-deficit hyperactivity disorder (ADHD), sleepwalking, nightmares, and parasomnias.[3][4]
Complications
Prognosis
- Men with RLS had a higher overall mortality and this association was independent of known risk factors.
- The increased mortality in RLS in men is more frequently associated with:
References
- ↑ Bogan RK, Cheray JA (2013). "Restless legs syndrome: a review of diagnosis and management in primary care". Postgrad Med. 125 (3): 99–111. doi:10.3810/pgm.2013.05.2636. PMID 23748511.
- ↑ Karroum EG, Golmard JL, Leu-Semenescu S, Arnulf I (2015). "Painful restless legs syndrome: a severe, burning form of the disease". Clin J Pain. 31 (5): 459–66. doi:10.1097/AJP.0000000000000133. PMID 25167326.
- ↑ 3.0 3.1 Rulong G, Dye T, Simakajornboon N (2018). "Pharmacological Management of Restless Legs Syndrome and Periodic Limb Movement Disorder in Children". Paediatr Drugs. 20 (1): 9–17. doi:10.1007/s40272-017-0262-0. PMID 28831753.
- ↑ 4.0 4.1 Facheris MF, Hicks AA, Pramstaller PP, Pichler I (2010). "Update on the management of restless legs syndrome: existing and emerging treatment options". Nat Sci Sleep. 2: 199–212. doi:10.2147/NSS.S6946. PMC 3630948. PMID 23616710.