Sjögren's syndrome historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
In 1892, Johann von Mikulicz-Radecki was to first to describe a patient with with enlargement of the parotid and lacrimal glands associated with a round-cell infiltrate and acinar atrophy.^[1]
In 1933, Henrik Sjögren was the first to describe 19 females with clinical and pathological manifestations of the Sjögren's syndrome.
In 1951, Sjögren published a paper describing 80 patients with keratoconjunctivitis sicca associated with Sjögren's syndrome.
In 1980, autoantibodies to the centromere proteins (CENP) were found in 40% of patients with Sjögren's syndrome.^[2]

In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

↑ Talal N (August 1992). "Sjögren's syndrome: historical overview and clinical spectrum of disease". Rheum. Dis. Clin. North Am. 18 (3): 507–15. PMID 1496158.
↑ Fritzler, Marvin J.; Rattner, Jerome B.; Luft, LeeAnne M.; Edworthy, Steven M.; Casiano, Carlos A.; Peebles, Carol; Mahler, Michael (2011). "Historical perspectives on the discovery and elucidation of autoantibodies to centromere proteins (CENP) and the emerging importance of antibodies to CENP-F". Autoimmunity Reviews. 10 (4): 194–200. doi:10.1016/j.autrev.2010.09.025. ISSN 1568-9972.