Reactive arthritis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The symptoms of reactive arthritis usually develop after 1-3 weeks of initial infection (in another part of the body) and start with symptoms such as malaise, fatigue, and fever.
Majority of the patients have a self limited course with complete healing within 3-12 months.
If left untreated, patients with reactive arthritis may progress to develop myalgias and joint pain especially in the lower extremities. Over the course of time, patient develops urethritis and conjunctivitis.
Urethritis presents with dysuria, increased frequency, urgency, and urethral discharge whereas conjunctivitis leads to pain, burning, and tearing sensation in eyes.