Undifferentiated connective tissue disease natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of undifferentiated connective tissue disease(UCTD)usually are similar to connective tissue diseases but couldn't complete the criteria for their definitive diagnosis.
- If left untreated, 24.3-33% of patients with UCTD may progress to develop manifestations of well defined connective tissue disease such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome.[1][2]
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- [Complication 3]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Danieli MG, Fraticelli P, Salvi A, Gabrielli A, Danieli G (1998). "Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD". Clin. Rheumatol. 17 (3): 195–201. PMID 9694051.
- ↑ Cavazzana I, Franceschini F, Belfiore N, Quinzanini M, Caporali R, Calzavara-Pinton P, Bettoni L, Brucato A, Cattaneo R, Montecucco C (2001). "Undifferentiated connective tissue disease with antibodies to Ro/SSa: clinical features and follow-up of 148 patients". Clin. Exp. Rheumatol. 19 (4): 403–9. PMID 11491495.