Acute promyelocytic leukemia history and symptoms
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Differentiating Acute promyelocytic leukemia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Signs and symptoms of acute promyelocytic leukemia are similar to other forms of leukemia, but bleeding and hemorrhagic events are more specific for acute promyelocytic leukemia since these patients are more likely to present with disseminated intravascular coagulation (coagulopathy).
Symptoms
Symptoms include
- Fever
- Fatigue
- Weight loss
- Loss of appetite
- Shortness of breath with exertion
- Anemia
- Easy bruising from thrombocytopenia and coagulopathy
- Mucosal bleeding from thrombocytopenia and coagulopathy
- Petechiae (flat, pin-head sized spots under the skin caused by bleeding)
- Bone and joint pain
- Persistent or frequent infections (from lack of normal white blood cells)