Chronic myelogenous leukemia risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
The most potent risk factor in the development of chronic myelogenous leukemia is ionizing radiation; for example, increased rates of CML were seen in people exposed to the atomic bombings of Hiroshima and Nagasaki. Other risk factors include formaldehyde, obesity, and smoking.[1][2]
Factors that increase the risk of chronic myelogenous leukemia:
- Older age
- Being male
- Radiation exposure, such as radiation therapy for certain types of cancer
- Family history is not a risk factor: The chromosome mutation that leads to chronic myelogenous leukemia isn't passed from parents to offspring. This mutation is believed to be acquired, meaning it develops after birth.
PMID:25814090
Common Risk Factors
Less common Risk Factors
References
- ↑ Moloney WC (1987). "Radiogenic leukemia revisited". Blood. 70 (4): 905–8. PMID 3477299.
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/staging/?region=ab