Renal tubular acidosis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Laboratory Findings

Laboratory Findings
Common laboratory findings		Other tests to consider
Test	Finding	Test	Finding
Serum HCO3	↓	Serum aldosterone	Low in aldosterone deficiency states Normal/ high in aldosterone resistance
Serum Chloride	↑	Urine anion gap	Absence of ammonia
Serum Na	Normal	Measurement of fractional urine bicarbonate excreation	Bicarbonateuria in proximal RTA
Serum Potassium	Variable	Furesimide test	pH >5.5 and elevated potassium (distal RTA) pH >5.5 and normal potassium (aldosterone deficiency)
Arterial Ph	↓	Urine glucose	Urine glucose + Serum glucose normal Fanconi syndrome
Serum anion gap	Normal	Fractional excretion of amino acids
Urine Ph	>5.5	Urine HCO3 infusion	PCO2 does not rise in distal RTA