Polyarteritis nodosa other imaging findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.
Overview
Other Imaging Findings
Arteriography
- Arteriography is the best imaging study to diagnosis of PAN.
- Findings on an arteriography diagnostic of PAN include:[1][2]
- Microaneurysms
- Pathognomic finding seen in 60-80% patients.
- Caused by rupture of a vessel wall due to necrotizing inflammatory process.
- Most commonly seen at the branching points and bifurcations of arteries.
- Microaneurysms are usually more than 10 in number.
- Size: 2-5mm
- Saccular aneurysms
- Size: 1-5mm
- Seen in small and medium sized vessels.
- Tortuous vessels showing:
- Irregular lumina
- Segmental luminal narrowing or dilatation
- Infarctions
- Vascular irregularity
- Segmental occlusions
- Microaneurysms
References
- ↑ Ewald EA, Griffin D, McCune WJ (October 1987). "Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa". J. Rheumatol. 14 (5): 952–6. PMID 2892931.
- ↑ Stanson AW, Friese JL, Johnson CM, McKusick MA, Breen JF, Sabater EA, Andrews JC (2001). "Polyarteritis nodosa: spectrum of angiographic findings". Radiographics. 21 (1): 151–9. doi:10.1148/radiographics.21.1.g01ja16151. PMID 11158650.