Polyarteritis nodosa other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.

Overview

Other Imaging Findings

Arteriography

  • Arteriography is the best imaging study to diagnosis of PAN.
  • Findings on an arteriography diagnostic of PAN include:[1][2][3]
    • Microaneurysms
      • Pathognomic finding seen in 60-80% patients.
      • Caused by rupture of a vessel wall due to necrotizing inflammatory process.
      • Most commonly seen at the branching points and bifurcations of arteries.
      • Microaneurysms are usually more than 10 in number.
      • Size: 2-5mm
    • Saccular aneurysms
      • Size: 1-5mm
      • Seen in small and medium sized vessels.
    • Tortuous vessels showing:
      • Irregular lumina
      • Segmental luminal narrowing or dilatation
      • Infarctions
      • Vascular irregularity
      • Segmental occlusions

References

  1. Ewald EA, Griffin D, McCune WJ (October 1987). "Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa". J. Rheumatol. 14 (5): 952–6. PMID 2892931.
  2. Stanson AW, Friese JL, Johnson CM, McKusick MA, Breen JF, Sabater EA, Andrews JC (2001). "Polyarteritis nodosa: spectrum of angiographic findings". Radiographics. 21 (1): 151–9. doi:10.1148/radiographics.21.1.g01ja16151. PMID 11158650.
  3. Stone JH (October 2002). "Polyarteritis nodosa". JAMA. 288 (13): 1632–9. PMID 12350194.

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