Renal tubular acidosis history and symptoms

	Renal tubular acidosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

The clinical manifestations of renal tubular acidosis depend upon the underlying etiology and type of acidosis.

Type of RTA
Distal renal tubular acidosis	Recessive form	Infancy	Severe hyperchloremic metabolic acidosis (serum bicarbonate levels may decrease below 10 mEq/L) Moderate to severe hypokalemia (serum potassium ≤ 3.0 mEq/L) Nephrocalcinosis Vomiting Dehydration Poor growth Rickets
Distal renal tubular acidosis	Dominant form	Adults	Common initial finding is renal stone or nephrocalcinosis Mild or no acidosis Mild to moderate hypokalemia Poor growth Bone disease CKD
Proximal renal tubular acidosis
Mixed renal tubular acidosis (Type 3)
Aldosterone deficiency or resistance (Type 4)