Polycystic kidney disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian,Yazan Daaboul
Overview
Common clues for ADPKD on history include flank or back pain, nocturia and polyuria, headache and family history of renal failure or diagnosed renal cystic diseases.
History
Early ADPKD is asymptomatic and clinical diagnosis is usually with family history and imaging. Common symptoms at presentation include:[1][2]
- Flank/Back pain due to an enlarging cyst, cyst infection or hemorrhage, nephrolithiasis, and pyelonephritis.
- Headache due to hypertension
- Polyuria and nocturia due to loss of concentrating ability
- Hematuria
- Dyspnea, early satiety, and obstructive jaundice due to enlarging hepatic cysts
Other important clues on history include:
- Detailed family history of renal failure and cystic diseases
- Detailed family history of intracranial aneurysms and aneurysmal rupture to assess patient risk
History and Symptoms
- The majority of patients with [disease name] are asymptomatic.
OR
- The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
- Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History
Patients with polycystic kidney disease may have a positive history of:
- Fatigue/weakness/malaise
- Blood in urine
- Flank/back pain
- Headache from hypertension
Common Symptoms
Common symptoms of polycystic kidney disease include:
- Flank/back pain
- Hematuria
- Hypertension
Less Common Symptoms
Less common symptoms of [disease name] include
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]
References
- ↑ Gabow PA (1993). "Autosomal dominant polycystic kidney disease". N Engl J Med. 329 (5): 332–42. doi:10.1056/NEJM199307293290508. PMID 8321262.
- ↑ Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.