Nephritic syndrome historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian
Overview
The symptoms of glomerulonephritis were first described by Richard Bright in 1827 when he discovered that several patients died with generalized edema were found to have renal disease. It was not until 1914 that Volhard and Fahr classified renal diseases in Die Brightsche Nierenkrankheit to 3 main categories: nephroses, nephritis, and arteriosclerotic disease. Acute post-streptococcal glomerulonephritis is thus considered the earliest nephritic syndrome to be described. In 1908, C.F. Wahrer described an epidemic of hemorrhagic nephritis preceded by scarlet fever in 35 patients. Epidemics of nephritis continued in 1915 among British troops during World War I. Clinical and pathological findings from both epidemics were similar. Hemolytic streptococci were isolated from cultures of the oropharynx in many patients.
Historical Perspective
- In 1827, Richard Bright was the first to discribe the symptoms of glomerulonephritis when he discovered that several patients died with generalized edema were found to have renal disease.[1]
- In 1908, C.F. Wahrer described an epidemic of hemorrhagic nephritis preceded by scarlet fever in 35 patients.
- In 1914, Volhard and Fahr classified renal diseases in Die Brightsche Nierenkrankheit to 3 main categories: nephroses, nephritis, and arteriosclerotic disease.[2]
- Acute post-streptococcal glomerulonephritis is considered the earliest nephritic syndrome to be described.
- In 1915, Epidemics of nephritis continued among the British troops during World War I.[3]
References
- ↑ Bright, R (1827–1831). Reports of Medical Cases, Selected with a View of Illustrating the Symptoms and Cure of Diseases by a Reference to Morbid Anatomy, vol. I. London: Longmans.
- ↑ Volhard, F (1914). Die Brightsche Nierenkrankheit. Springer.
- ↑ RAMMELKAMP CH, WEAVER RS (1953). "Acute glomerulonephritis, the significance of the variations in the incidence of the disease". J Clin Invest. 32 (4): 345–58. doi:10.1172/JCI102745. PMC 438348. PMID 13052693.