Nephrotic syndrome historical perspective
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Overview
In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy. In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.
Historical Perspective
- In 1484, Cornelus Roelans of Belgium described a child with “whole body swelling” and nephropathy.
- In 1722, Theodore Zwinger of Basel described nephrotic syndrome in children, with decreased urine out put due to “obstruction and compression of the tubules of the kidney.”
- In 1827, Richard Bright described the triad of generalized edema, proteinuria, and kidney disease, as features of nephrotic syndrome.
- In 1905, Müller described the term of "nephrosis" for non-inflammatory kidney diseases.