Myeloproliferative neoplasm risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
There are no established risk factors for myeloproliferative neoplasm.
Risk factors
- Autoimmunity: A prior history of autoimmune disease is associated with a risk for developing myeloproliferative neoplasms.[1] There is specifically an increased risk of myeloproliferative neoplasm is patients with:
- Crohn's disease: This carries a 2.9-fold increased risk.
- Immune thrombocytopenia purpura: This carries a 1.8-fold increased risk.
- Polymyalgia rheumatica: This carries a 1.7-fold increased risk.
- Giant cell arteritis: This carries a 5.9-fold increased risk.
- Reiter's reactive arthritis: This carries a 15.9-fold increased risk.
- Aplastic anemia: This carries a 7.8-fold increased risk.
References
- ↑ Kristinsson SY, Landgren O, Samuelsson J, Björkholm M, Goldin LR (2010). "Autoimmunity and the risk of myeloproliferative neoplasms". Haematologica. 95 (7): 1216–20. doi:10.3324/haematol.2009.020412. PMC 2895049. PMID 20053870.