Hydronephrosis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

Common risk factors in the development of hydronephrosis include renal calculi, external compression from abdominal and pelvic masses and tumors such as prostate enlargement and cancer, cervical cancer, diabetes mellitus and neurogenic bladder, congenital anomalies of the kidney and urinary tract (CAKUT) such as vesicoureteric reflux, ureteropelvic junction obstruction and posterior urethral valves.

Common Risk Factors

  • Common risk factors in the development of hydronephrosis include:[1][2][3][4][5][6]
    • Renal calculi (eg, kidney stones, ureteral stones, and bladder stones)
    • Prostate enlargement and prostate cancer
    • Pelvic and retroperitoneal masses and tumors compressing renal structures (eg, ovarian cysts, tuboovarian abscess, pelvic prolapse, retroperitoneal fibrosis, endometriosis and abdominal malignancies)
    • Pregnancy
    • Trauma
    • Pelvic radiation
    • Strictures
    • Neurogenic bladder
    • Urinary tract infection
    • Congenital anomalies of the kidney and urinary tract that can lead to hydronephrosis include
      • Vesicourethral reflux
      • Ureteropelvic junction obstruction
      • Posterior urethral valves
      • Prune belly syndrome
      • Primary bladder neck obstruction


References

  1. Iravani O, Tay EW, Bay BH, Ng YK (December 2014). "Unilateral ureteric stone associated with gross hydronephrosis and kidney shrinkage: a cadaveric report". Anat Cell Biol. 47 (4): 267–70. doi:10.5115/acb.2014.47.4.267. PMC 4276901. PMID 25548725.
  2. Gormley EA (November 2010). "Urologic complications of the neurogenic bladder". Urol. Clin. North Am. 37 (4): 601–7. doi:10.1016/j.ucl.2010.07.002. PMID 20955911.
  3. Riyach O, Ahsaini M, Kharbach Y, Bounoual M, Tazi MF, El Ammari JE, Mellas S, Fassi Mel J, Khallouk A, Farih MH (February 2014). "Bilateral ureteral obstruction revealing a benign prostatic hypertrophy: a case report and review of the literature". J Med Case Rep. 8: 42. doi:10.1186/1752-1947-8-42. PMC 3930078. PMID 24513237.
  4. Krajewski W, Wojciechowska J, Dembowski J, Zdrojowy R, Szydełko T (August 2017). "Hydronephrosis in the course of ureteropelvic junction obstruction: An underestimated problem? Current opinions on the pathogenesis, diagnosis and treatment". Adv Clin Exp Med. 26 (5): 857–864. PMID 29068584.
  5. Rodriguez MM (2014). "Congenital Anomalies of the Kidney and the Urinary Tract (CAKUT)". Fetal Pediatr Pathol. 33 (5–6): 293–320. doi:10.3109/15513815.2014.959678. PMC 4266037. PMID 25313840.
  6. Muram D, Oxorn H, Curry RH, Drouin P, Walters JH (February 1981). "Postradiation ureteral obstruction: a reappraisal". Am. J. Obstet. Gynecol. 139 (3): 289–93. PMID 7468696.


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