Myeloproliferative neoplasm ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]Shyam Patel [3]

Overview

Abdominal ultrasound may be helpful in the diagnosis of myeloproliferative neoplasm. Findings on abdominal ultrasound suggestive of myeloproliferative neoplasm include enlarged lymph nodes, splenomegaly, and hypodense liver lesions.

Abdominal Ultrasound

The role of abdominal ultrasound is to facilitate assessment of the spleen and liver. Patients with polycythemia vera or other myeloproliferative neoplasms frequently have enlarged spleens. Ultrasound allows for quantitative assessment of the spleen size. It can also detect liver enlargement, or hepatosplenomegaly. Abdominal fluid such as ascites can also be detected.

Lower Extremity Ultrasound

Lower extremity ultrasound is particularly useful in patients who are suspected of having deep vein thrombosis, which is commonly found in patients with polycythemia vera. Ultrasonography of the deep veins is indicated for patients with polycythemia vera who develop leg swelling, erythema, or pain.

Upper Extremity Ultrasound

In rare cases, polycythemia vera can result in upper extremity thrombosis. Upper extremity ultrasonography can help with diagnosis of an upper extremity deep vein thrombosis.