Hypercalcemia overview
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Hypercalcemia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hypercalcemia On the Web |
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American Roentgen Ray Society Images of Hypercalcemia |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hypercalcemia (in UK English Hypercalcaemia) is an elevated calcium level in the blood. (Normal range: 9-10.5 mg/dL or 2.2-2.6 mmol/L). It can be an asymptomatic laboratory finding, but because an elevated calcium level is often indicative of other diseases, a diagnosis should be undertaken if it persists. It can be due to excessive skeletal calcium release, increased intestinal calcium absorption, or decreased renal calcium excretion.
- Calcium is the most abundant mineral in the the body
- 99% of the calcium in the body is stored in the bone
- Calcium in the plasma is either ionized or protein-bound and readily available for use
- An increase in total plasma calcium concentration above 10.4 mg/dL signifies hypercalcemia
- Serum concentration is regulated through parathyroid hormone (PTH), vitamin D and calcitonin