Membranous glomerulonephritis diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- The page name should be "[Disease name] diagnostic study of choice", with only the first letter of the title capitalized. Note that the page is called "Diagnostic study of choice."
- Goal:
- To describe the most efficient/sensitive/specific test that is utilized for diagnosis of [disease name].
- To describe the gold standard test for the diagnosis of [disease name].
- To describe the diagnostic criteria, which may be based on clinical findings, physical exam signs, pathological findings, lab findings, findings on imaging, or even findings that exclude other diseases.
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- Remember to follow the same format and capitalization of letters as outlined in the template below.
- You should include the name of the disease in the first sentence of every subsection.
Diagnostic Study of Choice
Template statements
Gold standard/Study of choice:
- Biopsy is the gold standard test for the diagnosis of membranous glomerulonephritis.
- The complete blood count, urinalysis, 24 hour urine collection should be performed when:
- The patient presented with signs of proteinurea and hypertension.
- A positive [test] is detected in the patient.
- Biopsy is the gold standard test for the diagnosis of membranous glomerulonephritis.
The diagnostic study of choice for membranous glomerulonephritis are:
- chemistry panel,
- complete blood count,
- urinalysis,
- 24 hours urine collection,
- creatinine clearance,
- urine albumin,
- ANA,
- anti-doublestandard DNA,
- anti-SM,
- anti Ro/SSA,
- anti La/SSB,
- serum C3 and C4 Complement levels.
- Chest CT,
- Anti PLA2Rantibody.
Diagnostic Test:
Biopsy is confirmatory of membranous glomerulonephritis.
Sequence of Diagnostic Studies
The urinalysis and comprehensive chemistry panel should be performed when:
- The patient presented with signs of hypertension and proteinurea.
- A positive ANA, anti dsDNA is detected in the patient, to confirm the diagnosis.
Diagnostic Criteria
- There are no established criteria for the diagnosis of membranous glomerulonephritis.