Membranous glomerulonephritis overview
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Membranous glomerulonephritis Microchapters |
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Differentiating Membranous glomerulonephritis from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
- Membranous glomerulonephritis was first discovered by David Jones, renal pathologist from Syracuse University in New York, in 1957.
Classification
- There is no established system for the classification of MGN. however it can be divided in two groups based on etiology of MGN.
Pathophysiology
- It is thought that MGN is mediated by genetic factors and environmental factors.
Causes
- The main causes of Membranous Glomerulonephritis are Infectious causes like Hepatitis B, drugs like captopril and autoimmune diseases like systemic lupus erythematosus.
Differentiating Hereditary pancreatitis from Other Diseases
- MGN must be differentiated from other diseases that cause proteinuria, weight loss, and renal failure, such as MPGN, MCD, and FSGC.
Epidemiology and Demographics
- The Incidence rate of Membranous Glomerulonephritis is 27 per 100.000.
- The Prevalence rate of Membranous Glomerulonephritis is 690 per 100,000
Risk Factors
- The most potent risk factor in the development of [disease name] is drugs. Other risk factors include penicilliamine and captopril.
Screening
- There is insufficient evidence to recommend routine screening for membranous glomerulonephritis.