Diabetic nephropathy causes

Diabetic nephropathy Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Diabetes mellitus both type1 and type 2 is the major cause. It is thought to be due to hyperfiltration through the renal glomeruli. The chances of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. these observations have been seen in both type 1 and type 2 diabetes. The genetic basis underlying the heritability of diabetic nephropathy is not known.

Causes

• Diabetes, type 1 or 2
• Persistent, uncontrolled hyperglycemia
• Hypertension in the presence of diabetes.
• Diabetes with smoking
• High blood cholesterol and diabetes
• Genetic factors