Thrombotic thrombocytopenic purpura classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]

Classification

• Hereditary: Congenital TTP, inherited TTP, familial TTP, Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34

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• Acquired: Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.