Hemolytic-uremic syndrome historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

Discovery

  • HUS was first described by Gasser and colleagues in paper published in 1955[1] .
  • The association between Shiga-toxin-producing bacteria and HUS was made during 35 years ago[1].
  • In 1983, Karmali and colleagueswas the first to discover the association between Escherichia coli and the development of HUS[1].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Outbreaks

There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

The following are a few famous cases of disease name:

References

  1. 1.0 1.1 1.2 Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter |month= ignored (help)

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