Stevens-Johnson syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

  • The incidence of SJS is approximately 2-7 per 1000,000 individuals per year.[1]
  • The incidences of SJS, SJS-TEN, and TEN were found to be a mean 5.3, 0.8, and 0.4 cases per million children per year in the US[2]
  • The mean estimated incidences of SJS, SJS/TEN, and TEN were found to be 9.2, 1.6, and 1.9 per million adults per year in the US[3]

Case-fatality rate/Mortality rate

  • Between years 2009-2012, the Mean adjusted mortality was 4.8% for SJS, 19.4% for SJS/TEN, and 14.8% for TEN[4]

Age

  • Patients of all age groups may develop SJS.

Race

  • The incidence of SJS might be higher in Non White/Multiracial people as compared to White"Redirecting".

Gender

  • Women are more commonly affected by SJS than males"Redirecting"..

References

  1. Strom BL, Carson JL, Halpern AC, Schinnar R, Snyder ES, Shaw M; et al. (1991). "A population-based study of Stevens-Johnson syndrome. Incidence and antecedent drug exposures". Arch Dermatol. 127 (6): 831–8. PMID 2036028.
  2. Hsu DY, Brieva J, Silverberg NB, Paller AS, Silverberg JI (2017). "Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States". J Am Acad Dermatol. 76 (5): 811–817.e4. doi:10.1016/j.jaad.2016.12.024. PMC 5502094. PMID 28285784.
  3. Hsu DY, Brieva J, Silverberg NB, Silverberg JI (2016). "Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults". J Invest Dermatol. 136 (7): 1387–1397. doi:10.1016/j.jid.2016.03.023. PMID 27039263.
  4. Hsu DY, Brieva J, Silverberg NB, Silverberg JI (2016). "Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults". J Invest Dermatol. 136 (7): 1387–1397. doi:10.1016/j.jid.2016.03.023. PMID 27039263.

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