Thrombotic thrombocytopenic purpura classification

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Classification

TTP may be classified into several subtypes based on:

  1. autoantibody against ADAMTS13

Congenital TTP Inherited TTP familial TTP Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34

  1. gene mutations of ADAMTS13

References

Template:WHTemplate:WSEditor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]

Overview

References

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  • Hereditary:
  • Congenital TTP
  • Inherited TTP
  • familial TTP
  • Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 [1].
  • Acquired: Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.

References

  1. Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi, Akira Yoshioka, Taei Matsui & Koiti Titani (2002). "Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome". International journal of hematology. 75 (1): 25–34. PMID 11843286. Unknown parameter |month= ignored (help)

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