Thrombotic thrombocytopenic purpura classification
Classification
TTP may be classified into several subtypes based on:
- autoantibody against ADAMTS13
Congenital TTP Inherited TTP familial TTP Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34
- gene mutations of ADAMTS13
References
Template:WHTemplate:WSEditor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]
Overview
References
- Hereditary:
- Congenital TTP
- Inherited TTP
- familial TTP
- Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 [1].
- Acquired: Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.
References
- ↑ Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi, Akira Yoshioka, Taei Matsui & Koiti Titani (2002). "Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome". International journal of hematology. 75 (1): 25–34. PMID 11843286. Unknown parameter
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