Palmar plantar erythrodysesthesia classification

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Overview

Classification

Palmar Plantar Erythrodysesthesia may be classified according to toxicity or severity of symptoms into 4 grades.

TOXICITY GRADING OF PPE [1]
GRADES
1 Mild erythema, edema, or desquamation that doesn't interfere with daily activities
2 Blisters or ulcers <2 cm diameter; Erythema edema or desquamation complication but not precluding daily activities.
3 Blisters, ulcers or edema that interfere with daily activities; Person cannot wear regular clothing.
4 Lesions complicated with infection; hospitalized or bed ridden


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