Amyotrophic lateral sclerosis diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Equal emphasis on both electromyogram (EMG) and clinical abnormalitie are the gold standard method for the diagnosis of amyotrophic lateral sclerosis. EMG and nerve conduction studies are most sensitive to detecting the disease and can quantify its trademark characteristic of LMN degeneration. Magnetic resonance imaging (MRI) studies of the brain and spinal cord are the most useful neuroimaging technique in ALS mainly to exclude syndromes that mimic ALS.

Diagnostic Study of Choice

Study of choice

• Equal emphasis on both electromyogram (EMG) and clinical abnormalitie are the gold standard method for the diagnosis of amyotrophic lateral sclerosis.

• EMG and nerve conduction studies are most sensitive to detecting the disease and can quantify its trademark characteristic of LMN degeneration.

• Magnetic resonance imaging (MRI) studies of the brain and spinal cord are the most useful neuroimaging technique in ALS mainly to exclude syndromes that mimic ALS.