Amyotrophic lateral sclerosis diagnostic study of choice
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Differentiating Amyotrophic lateral sclerosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Equal emphasis on both electromyogram (EMG) and clinical abnormalitie are the gold standard method for the diagnosis of amyotrophic lateral sclerosis. EMG and nerve conduction studies are most sensitive to detecting the disease and can quantify its trademark characteristic of LMN degeneration. Magnetic resonance imaging (MRI) studies of the brain and spinal cord are the most useful neuroimaging technique in ALS mainly to exclude syndromes that mimic ALS.
Diagnostic Study of Choice
Study of choice
- Equal emphasis on both electromyogram (EMG) and clinical abnormalitie are the gold standard method for the diagnosis of amyotrophic lateral sclerosis.[1][2]
- EMG and nerve conduction studies are most sensitive to detecting the disease and can quantify its trademark characteristic of LMN degeneration.[1][3][4][5]
- Magnetic resonance imaging (MRI) studies of the brain and spinal cord are the most useful neuroimaging technique in ALS mainly to exclude syndromes that mimic ALS.[1][5]
References
- ↑ 1.0 1.1 1.2 Zarei S, Carr K, Reiley L, Diaz K, Guerra O, Altamirano PF; et al. (2015). "A comprehensive review of amyotrophic lateral sclerosis". Surg Neurol Int. 6: 171. doi:10.4103/2152-7806.169561. PMC 4653353. PMID 26629397.
- ↑ Mills KR (2011). "Detecting fasciculations in amyotrophic lateral sclerosis: duration of observation required". J Neurol Neurosurg Psychiatry. 82 (5): 549–51. doi:10.1136/jnnp.2009.186833. PMID 20462913.
- ↑ Costa J, Swash M, de Carvalho M (2012). "Awaji criteria for the diagnosis of amyotrophic lateral sclerosis:a systematic review". Arch Neurol. 69 (11): 1410–6. doi:10.1001/archneurol.2012.254. PMID 22892641.
- ↑ de Carvalho M, Dengler R, Eisen A, England JD, Kaji R, Kimura J; et al. (2008). "Electrodiagnostic criteria for diagnosis of ALS". Clin Neurophysiol. 119 (3): 497–503. doi:10.1016/j.clinph.2007.09.143. PMID 18164242.
- ↑ 5.0 5.1 Hardiman O, van den Berg LH, Kiernan MC (2011). "Clinical diagnosis and management of amyotrophic lateral sclerosis". Nat Rev Neurol. 7 (11): 639–49. doi:10.1038/nrneurol.2011.153. PMID 21989247.