Optic neuritis
|
WikiDoc Resources for Optic neuritis |
|
Articles |
|---|
|
Most recent articles on Optic neuritis Most cited articles on Optic neuritis |
|
Media |
|
Powerpoint slides on Optic neuritis |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Optic neuritis at Clinical Trials.gov Trial results on Optic neuritis Clinical Trials on Optic neuritis at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Optic neuritis NICE Guidance on Optic neuritis
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Optic neuritis Discussion groups on Optic neuritis Patient Handouts on Optic neuritis Directions to Hospitals Treating Optic neuritis Risk calculators and risk factors for Optic neuritis
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Optic neuritis |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Historical Perspective
Optic nerve disorders were not reliably diagnosed until the late nineteenth century when ophthalmoscopy became part of the ophthalmic examination. By the early 1900's, all of the salient clinical features of optic neuritis and its relationship to "systemic sclerosis" were recognized, but there was much controversy and misunderstanding about its differential diagnosis, pathogenesis, and possible treatment. During the twentieth century, physicians began to distinguish optic neuritis from infectious, hereditary, toxic, nutritional, and ischemic optic neuropathies. The development of magnetic resonance imaging and the results from recent clinical trials have enhanced our understanding of the relationship between optic neuritis and multiple sclerosis. The next decade holds the promise of further elaborating the pathogenesis and treatment of optic neuritis.
Discovery
- [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in late nineteenth century when ophthalmoscopy became part of the ophthalmic examination.
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Outbreaks
There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Classification
Pathophysiology
Causes
Differentiating Optic Neuritis from other Diseases
Epidemiology and Demographics
Optic neuritis typically affects young adults ranging from 18–45 years of age, with a mean age of 30–35 years. There is a strong female predominance. The annual incidence is approximately 5/100,000, with a prevalence estimated to be 115/100,000.[1]