Multiple myeloma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [3] Shyam Patel [4]
Overview
In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.[1] The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.[2][3] Multiple myeloma is the second most common blood cancer after non-Hodgkin's lymphoma and 14th most common cancer overall in United States.[4][2][3] Males are more commonly affected with multiple myeloma than females; the male to female ratio is approximately 1.54 to 1.[3][5] Multiple myeloma usually affects individuals of the African American race. Asian individuals are less likely to develop multiple myeloma.[3] The incidence of multiple myeloma increases with age.
Epidemiology and Demographics
Key Statistics
| Estimated New Cases in 2018 | 30,770 |
|---|---|
| % of All New Cancer Cases | 1.8% |
| Estimated Deaths in 2018 | 12,770 |
| % of All Cancer Deaths | 2.1% |
| 5 Years Survival Rate | 50.7%
2008-2014 |
| Adopted from National Cancer Institute[6] | |
| New Cases per 100,000 Persons by Race/Ethnicity & Sex | ||
|---|---|---|
| Race | Female | Male |
| All Races | 5.3 | 8.4 |
| White | 4.7 | 7.9 |
| Black | 11.6 | 15.9 |
| Asian / Pacific Islander | 3.1 | 4.9 |
| American Indian / Alaska Native | 5.5 | 6.2 |
| Hispanic | 5.0 | 7.6 |
| Non-Hispanic | 5.4 | 8.5 |
| Adopted from National Cancer Institute[6] | ||
| Percent of New Cases by Age Group | |
|---|---|
| Age | Percent of New cases |
| <20 | |
| 20-34 | 0.5% |
| 35-44 | 2.8% |
| 45-54 | 10.9% |
| 55-64 | 23.2% |
| 65-74 | 29.8% |
| 75-84 | 23.7% |
| >84 | 9.0% |
| Adopted from National Cancer Institute[6] | |
Incidence
- The age-standardized incidence rate of multiple myeloma worldwide is 1.5 per 100,000 persons per year.[7][6]
- According to age-adjusted rates based in 2011-2015, the incidence of multiple myeloma was approximately 6.7 per 100,000 individuals with a case-fatality rate of 3.3 per 100,000 in the United States.[1][6]
- In 2018, multiple myeloma will constitute approximately 1.8% of the estimated new cancer cases.[8][6]
- In 2018, the estimated deaths caused by multiple myeloma will constitute 2.1% of all cancer mortality cases.[2][6]
- In 2018, approximately 30,770 people will be diagnosed with multiple myeloma.
- In 2018, approximately 12,770 people die from multiple myeloma.[6]
- According to 2013-2015 data, approximately 0.8% of all people will have a diagnosis of multiple myeloma at some point during their lifetime in US.[6]
- According to an estimation in 2015, there were 124,733 people with myeloma living in the United States.[6]
- Multiple myeloma is the second most common hematologic malignancy, after non-Hodgkin lymphoma.[7]
- Since 1975, the overall multiple myeloma incidence has increased nearly 1 percent annually.[8]
- Solitary plasmacytoma accounts for approximately 5% of plasma cell neoplasms.[9]
Prevalance
- Myeloma is the 14th leading cause of cancer death in the United States.[2]
- In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.[2]
Age
- The incidence of multiple myeloma increases with age, and the median age at diagnosis is 65 to 70 years.[7]
Gender
- Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 1.54 to 1.[5]
- The incidence of solitary plasmacytoma in males to females is 2:1.[9]
Race
- Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer deaths.[2]
- The incidence of multiple myeloma in the African American population is more than the European American population.
- African Americans have a 2-fold higher age-standardized incidence rate of multiple myeloma than Caucasians.[7] The incidence of multiple myeloma in African Americans is 9.6 per 100,000 persons. The incidence of Caucasians is 4.1 per 100,000 persons.[7]
Gallery
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References
- ↑ 1.0 1.1 Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1 Accessed on September, 20th 2015
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
- ↑ 3.0 3.1 3.2 3.3 Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
- ↑ Collins, CD. (2005). "Problems monitoring response in multiple myeloma". Cancer Imaging. 5 Spec No A: S119–26. doi:10.1102/1470-7330.2005.0033. PMID 16361127.
- ↑ 5.0 5.1 Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 "Myeloma - Cancer Stat Facts".
- ↑ 7.0 7.1 7.2 7.3 7.4 Hong J, Lee JH (2016). "Recent advances in multiple myeloma: a Korean perspective". Korean J Intern Med. 31 (5): 820–34. doi:10.3904/kjim.2015.408. PMC 5016289. PMID 27604794.
- ↑ 8.0 8.1 A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma Accessed on September, 20th 2015
- ↑ 9.0 9.1 Jia R, Xue L, Liang H, Gao K, Li J, Zhang Z (2015). "Surgery combined with radiotherapy for the treatment of solitary plasmacytoma of the rib: a case report and review of the literature". J Cardiothorac Surg. 10: 125. doi:10.1186/s13019-015-0335-5. PMC 4605096. PMID 26464186.