Thymoma diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Khuram Nouman, M.D. [4]
Overview
Thymoma can be largely diagnosed by using radiological techniques.
Diagnostic Study of Choice
Investigations:[1]
- Posterior-anterior (PA) and lateral X-ray of the chest are helpful in diagnosing most of thymomas.
- Among the patients who present with clinical signs of myasthenia gravis (MG), the CT Scan is the test of choice for the diagnosis of Thymoma.
- CT Scan with IV contrast and magnetic resonance imaging are helpful in determining the vascularity of the thymoma and helps in safe surgical removal of large tumors.
- PET Scan is very valuable in diagnosing the cases of invasive malignant thymoma.
- Thallium 201 single photon emission computed tomography is useful to distinguish normal thymic tissue from hyperplastic tissue or thymoma
- Ultrasonically guided core needle biopsy is used to obtain larger tissue specimens for histological examination. Annessi and colleagues[2] were able to diagnose thymoma in all patients that had undergone anterior mediastinal core needle biopsy by ultrasonic guidance with a sensitivity and specificity of 100%.
References
- ↑ . doi:10.1016/j.athoracsur.2008.12.095]. Missing or empty
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(help) - ↑ Assaad, Margaret W.; Pantanowitz, Liron; Otis, Christopher N. (2007). "Diagnostic accuracy of image-guided percutaneous fine needle aspiration biopsy of the mediastinum". Diagnostic Cytopathology. 35 (11): 705–709. doi:10.1002/dc.20738. ISSN 8755-1039.