Pneumomediastinum historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
The condition was first described in 1819 by René Laennec.
Historical Perspective
Discovery
- The condition was first described in 1819 by René Laennec. [1][2]
- Later in 1939, Louis Hamman described primary or spontaneous pneumomediastinum which is why it is also known as Hamman's syndrome. He described a post-partum patient with subcutaneous emphysema and pneumomediastinum, a case known in current times as Hamman’s syndrome[3].
- Macklin and Macklin, in 1944 provided a sound explanation for pneumomediastinum, based on experiments conducted on cats: the increase of alveolar pressure causes them to rupture, therefore releasing air which in turn migrates through the peribronchial and perivascular sheaths to the mediastinum [4].
References
- ↑ Laënnec RTH. De l’auscultation médiate ou Traité du Diagnostic des Maladies des Poumon et du Coeur. 1st ed. Paris: Brosson & Chaudé; 1819.
- ↑ Roguin A (2006). "Rene Theophile Hyacinthe Laënnec (1781-1826): the man behind the stethoscope". Clinical medicine & research. 4 (3): 230–5. PMID 17048358.
- ↑ Hamman L. Spontaneous mediastinal emphysema. Bull Johns Hopkins Hosp 1939;64:1-21
- ↑ MACKLIN MADGE THURLOW; MACKLIN, CHARLES C. Medicine: December 1944 - Volume 23 - Issue 4 - ppg 281-358