Hodgkin's lymphoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

The most common symptoms of classic Hodgkin lymphoma include painless localized peripheral lymphadenopathy, B symptoms (fever, night sweats) Pruritus. Less common symptoms of Hodgkin's lymphoma include cough, chest pain, breathing problems, pain or feeling of fullness below the ribs, pain in lymph nodes after drinking alcohol, skin blushing or flushing, bone pain, and leg swelling.

History and Symptoms

• The presentation of Hodgkin lymphoma may vary depending on the location of tumor and organ involvement, mass size and stage of disease. Disease begins at a single site of the lymphatic system, generally a lymph node, and then progresses to next lymph nodes through lymphatic vessels before spreading to other sites and organs.
• The most common symptoms of Hodgkin's lymphoma include the following:

History

• Fatigue
• Fever (Pel-Ebstein fever) and chills
• Itching all over the body that cannot be explained
• Loss of appetite
• Soaking night sweats
• Weight loss that cannot be explained
• Painless swelling of the lymph nodes in the neck, axilla, or groin (swollen glands)

• Less common symptoms of Hodgkin's lymphoma include the following:

• Cough, chest pain, or breathing problems if there are swollen lymph nodes in the chest
• Pain or feeling of fullness below the ribs due to swollen spleen or liver
• Pain in lymph nodes after drinking alcohol
• Skin blushing or flushing
• Bone pain
• Swelling of legs may be caused by extra fluid if swollen lymph nodes are blocking the flow of lymph fluid

• Systemic symptoms such as fever and weight loss are known as B symptoms.

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