Sandbox:Preeti

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]

			Pathophysiology	Symptoms	History	Physical Examination	Laboratory Findings
							Immunochemistry	Blood work	Biospy/CT/CXR
Infections	Bacterial	Syphilis
		Brucellosis
	Viral	infectious mononucleosis
		cytomegalovirus
		human immunodeficiency virus
		cat scratch fever
	Mycobacterial	tuberculosis	Mostly in endemic areas Symptoms include productive cough,night sweats, fever and weight loss				Sputum smear positive for acid-fast bacilliand nucleic acid amplification tests (NAAT) is used on sputum or any sterile fluid for rapid diagnosis and is positive for mycobacteria.		CXR and CT demonstrates cavities in the upper lobe of the lung
	Parasitic	toxoplasmosis
Autoimmune	Systemic lupus erythematosus
	Sjögren's syndrome
	Hydantoin derivatives
	Sarcoidosis		More common in African-American females Often asymptomatic except for enlarged lymph nodes Associated with restrictive lung disease Erythema nodosum Lupus pernio (skin lesions on face resembling lupus) Bell palsy Epithelioid granulomas containing microscopic Schaumann and asteroid bodies						On CXR bilateral adenopathy and coarse reticular opacities are seen. CT of the chest demonstrates extensive hilar and mediastinal adenopathy Additional findings on CT include fibrosis (honeycomb, linear, or associated with bronchial distortion), pleural thickening, and ground-glass opacities. Biopsy of lung shows non-caseatinggranuloma
Neoplasms	Hodgkin's disease
	Chronic lymphocytic leukemia
	Small cell carcinoma of the lung
	Malignant histiocytosis
	Melanoma
	Germ cell neoplasms
Other conditions	Reactive lymphoid hyperplasia
	Lymphomatoid granulomatosis
	Dermatopathic lymphadenopathy
	Angioimmunoblastic lymphadenopathy
	Giant lymph node hyperplasia (Castleman disease)