Amyloidosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[3]

Overview

In amyloidosis, the range of symptoms depends on specific tissues and organs involved.^[1] Symptoms can be quite diverse.

History and Symptoms

History

Patients with amyloidosis may have a positive history of:^[2]

Dyspnea
Lethargy
Weight loss
Chest discomfort
Fevers or chills
Night sweats

Common Symptoms

Common symptoms in patients with primary amyloidosis include:^[2]

Bleeding tendency
Swelling of lower limbs
Frothy urine

Less Common Symptoms

Enlarged tongue sensation
Abdominal pain
Diarrhea
Peripheral neuropathy (nerve pain including numbness and tingling)

References

↑ Jerzykowska S, Cymerys M, Gil LA, Balcerzak A, Pupek-Musialik D, Komarnicki MA (2014). "Primary systemic amyloidosis as a real diagnostic challenge - case study". Cent Eur J Immunol. 39 (1): 61–6. doi:10.5114/ceji.2014.42126. PMC 4439975. PMID 26155101.
↑ ^2.0 ^2.1 Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.

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[pmid26155101-1] Jerzykowska S, Cymerys M, Gil LA, Balcerzak A, Pupek-Musialik D, Komarnicki MA (2014). "Primary systemic amyloidosis as a real diagnostic challenge - case study". Cent Eur J Immunol. 39 (1): 61–6. doi:10.5114/ceji.2014.42126. PMC 4439975. PMID 26155101.

[pmid24497558-2] 2.0 ^2.1 Mahmood S, Palladini G, Sanchorawala V, Wechalekar A (February 2014). "Update on treatment of light chain amyloidosis". Haematologica. 99 (2): 209–21. doi:10.3324/haematol.2013.087619. PMC 3912950. PMID 24497558.

[1]

[2]