Burkitt's lymphoma laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Laboratory tests for Burkitt's lymphoma include complete blood count (CBC), blood chemistry studies, immuno histochemistry, HIV blood test, flow cytometric analysis, and cytogenetics.
Laboratory Findings
Laboratory tests for Burkitt's lymphoma include:[1]
- Complete blood count[2]
- Blood chemistry studies include:
- HIV blood test
- Immuno histochemistry: CD19 +, CD20 +, CD22 +, CD79a +, Bcl-6 +, CD10 +, CD38 +, Mum-1 -, CD44 -, CD138 -, and Bcl-2-
- Flow cytometric analysis: (immunophenotype) CD19 +, CD20 +, CD22 +, and cytoplasmic terminal deoxynucleotidyl transferase (TdT) -
- Cytogenetics include:
- Giemsa banding
- Fluorescence in situ hybridization (FISH)
References
- ↑ Perkins AS, Friedberg JW (2008). "Burkitt lymphoma in adults". Hematology Am Soc Hematol Educ Program: 341–8. doi:10.1182/asheducation-2008.1.341. PMID 19074108.
- ↑ Ekemen S, Uzay A, Bassullu N, Dikicioglu-Cetin E, Matsuda K, Ince U; et al. (2018). "Does it take three to tango? An unsuspected multimorbidity of CD8+ T cell lymphoproliferative disorder, malaria, and EBV infection". Malar J. 17 (1): 349. doi:10.1186/s12936-018-2497-9. PMC 6173833. PMID 30290813.