Carcinoid syndrome classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Anum Gull M.B.B.S.[2]Parminder Dhingra, M.D. [3]

Classification

• Gastroenteropancreatic neuroendocrine tumors(GET-NETs) are located in different parts of GI tract.
• GET-NETs produce a number of secretory products, resulting in a wide range of clinical symptoms.
• Gastroenteropancreatic neuroendocrine tumors(GET-NETs) can be classified according to their location in GIT tract.

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Gastroenteropancreatic neuroendocrine tumors

	Foregut	Midgut	Hindgut
Location	Stomach Duodenum Bronchus Thymus	Jejunum Ileum Appendix Ascending colon	Transverse, Descending colon Sigmoid colon Rectum Genitourinary
Hormones produced	5-hydroxytryptophan Histamine, Multiple polypeptides	Serotonin Prostaglandins, Polypeptides	Variable
Possibility of carcinoid syndrome	Rare, and atypical when it happens	Classic	Rare