Barx homeobox 1

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

BARX homeobox 1 is a protein that in humans is encoded by the BARX1 gene.

Function

This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008].

Further reading

• Lowry RB, Gould DB, Walter MA, Savage PR (June 2007). "Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up". Am. J. Med. Genet. A. 143A (11): 1227–30. doi:10.1002/ajmg.a.31732. PMID 17486624.
• Krivicka-Uzkurele B, Pilmane M, Akota I (2008). "Barx1, growth factors and apoptosis in facial tissue of children with clefts". Stomatologija. 10 (2): 62–6. PMID 18708738.
• Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts". Genet. Med. 10 (9): 668–74. doi:10.1097/GIM.0b013e3181833793. PMC 2734954. PMID 18978678.
• Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC (July 2010). "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia". PLoS ONE. 5 (7): e11493. doi:10.1371/journal.pone.0011493. PMC 2901336. PMID 20634891.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.