TP53INP1

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene. In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein"

Interactions

TP53INP1 has been shown to interact with HIPK2 and p53.

Further reading

• Tomasini R, Samir AA, Pebusque MJ, et al. (2003). "P53-dependent expression of the stress-induced protein (SIP)". Eur. J. Cell Biol. 81 (5): 294–301. doi:10.1078/0171-9335-00248. PMID 12067065.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tomasini R, Samir AA, Carrier A, et al. (2003). "TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity". J. Biol. Chem. 278 (39): 37722–9. doi:10.1074/jbc.M301979200. PMID 12851404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hershko T, Chaussepied M, Oren M, Ginsberg D (2005). "Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F". Cell Death Differ. 12 (4): 377–83. doi:10.1038/sj.cdd.4401575. PMID 15706352.
• Tomasini R, Seux M, Nowak J, et al. (2006). "TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity". Oncogene. 24 (55): 8093–104. doi:10.1038/sj.onc.1208951. PMID 16044147.
• Jiang PH, Motoo Y, Garcia S, et al. (2006). "Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer". World J. Gastroenterol. 12 (5): 691–6. PMID 16521180.
• Ito Y, Motoo Y, Yoshida H, et al. (2007). "High level of tumour protein p53-induced nuclear protein 1 (TP53INP1) expression in anaplastic carcinoma of the thyroid". Pathology. 38 (6): 545–7. doi:10.1080/00313020601024094. PMID 17393983.
• Bernardo MV, Yelo E, Gimeno L, et al. (2007). "Identification of apoptosis-related PLZF target genes". Biochem. Biophys. Res. Commun. 359 (2): 317–22. doi:10.1016/j.bbrc.2007.05.085. PMID 17537403.