STS-1 (gene)

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For the 1981 spaceflight see: STS-1

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
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Ubiquitin-associated and SH3 domain-containing protein B is a protein that in humans is encoded by the UBASH3B gene.[1][2][3]

This gene encodes a protein that contains a ubiquitin associated protein domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.[3]

References

  1. Nagase T, Kikuno R, Ohara O (Feb 2002). "Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins". DNA Res. 8 (6): 319–27. doi:10.1093/dnares/8.6.319. PMID 11853319.
  2. Carpino N, Kobayashi R, Zang H, Takahashi Y, Jou ST, Feng J, Nakajima H, Ihle JN (Oct 2002). "Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein". Mol Cell Biol. 22 (21): 7491–500. doi:10.1128/MCB.22.21.7491-7500.2002. PMC 135669. PMID 12370296.
  3. 3.0 3.1 "Entrez Gene: STS-1 Cbl-interacting protein Sts-1".

Further reading