CD300LB (gene)

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

CD300 molecule like family member b is a protein that in humans is encoded by the CD300LB gene.

Function

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008].

Further reading

• Martínez-Barriocanal A, Sayós J (September 2006). "Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways". J. Immunol. 177 (5): 2819–30. PMID 16920917.
• Yamanishi Y, Kitaura J, Izawa K, Matsuoka T, Oki T, Lu Y, Shibata F, Yamazaki S, Kumagai H, Nakajima H, Maeda-Yamamoto M, Tybulewicz VL, Takai T, Kitamura T (January 2008). "Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells". Blood. 111 (2): 688–98. doi:10.1182/blood-2007-04-085787. PMID 17928527.
• Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M (April 2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Gasiorowski RE, Ju X, Hart DN, Clark GJ (January 2013). "CD300 molecule regulation of human dendritic cell functions". Immunol. Lett. 149 (1–2): 93–100. doi:10.1016/j.imlet.2012.10.005. PMID 23072861.
• Voss OH, Murakami Y, Pena MY, Lee HN, Tian L, Margulies DH, Street JM, Yuen PS, Qi CF, Krzewski K, Coligan JE (June 2016). "Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock". Immunity. 44 (6): 1365–78. doi:10.1016/j.immuni.2016.05.005. PMC 4917413. PMID 27261276.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.