AMP deaminase 2

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
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RefSeq (mRNA)

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RefSeq (protein)

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AMP deaminase 2 is an enzyme that in humans is encoded by the AMPD2 gene.[1][2]

High AMPD2 expression levels correlate with poor patient outcome and a proliferative tumor phenotype in undifferentiated pleomorphic sarcoma (UPS). [3]

References

  1. Mahnke-Zizelman DK, Sabina RL (Nov 1992). "Cloning of human AMP deaminase isoform E cDNAs. Evidence for a third AMPD gene exhibiting alternatively spliced 5'-exons". J Biol Chem. 267 (29): 20866–77. PMID 1400401.
  2. "Entrez Gene: AMPD2 adenosine monophosphate deaminase 2 (isoform L)".
  3. Orth MF, Gerke JS, Knösel T, Altendorf-Hofmann A, Musa J, Alba-Rubio R, et al. (September 2018). "Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma". International Journal of Cancer. doi:10.1002/ijc.31903. PMID 30267407.

External links

Further reading