CYREN (cell cycle regulator of NHEJ) is a protein which prevents classical non-homologous end joining, a method of repair of double-stranded DNA breaks.[1] This protein is therefore important in regulating DNA repair.
References
- ↑ Arnoult, N; Correia, A; Ma, J; Merlo, A; Garcia-Gomez, S; Maric, M; Tognetti, M; Benner, CW; Boulton, SJ; Saghatelian, A; Karlseder, J (20 September 2017). "Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN". Nature. 549 (7673): 548–552. doi:10.1038/nature24023. PMID 28959974.