Fibroadenoma natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Most patients with fibroadenoma are asymptomatic. If left untreated, patients with fibroadenoma may progress to develop a painless, mobile, and well-circumscribe breast lump. Fibroadenoma is a benign tumor that rarely develops any complications. Fibroadenomas commonly enlarge during pregnancy and involute after the age of menopause. The prognosis is generally excellent, and the 5-year survival rate of patients with fibroadenoma is almost equal to the normal population.[1]
Natural History
- Most patients with fibroadenoma are asymptomatic. If left untreated, patients with fibroadenoma may progress to develop a painless, mobile, and well-circumscribe breast lump.[1]
- The risk of malignant transformation is extremely low, where it has been reported in only 0.0125% of the cases.
- Fibroadenomas commonly enlarge during pregnancy and involute after the age of menopause.
- More than 70% of fibroadenomas present as a single mass, and 10%–25% of fibroadenomas present as multiple masses.[2]
Complications
- Fibroadenoma is a benign tumor that rarely develops any complications.[1]
Prognosis
- The prognosis is generally excellent, and the 5-year survival rate of patients with fibroadenoma is almost equal to the normal population.[1]
- In adolescents, the mass regresses completely between 10 and 40% of the time.[3]
References
- ↑ 1.0 1.1 1.2 1.3 Fibroadenoma. Radiopaedia (2015) http://radiopaedia.org/articles/fibroadenoma-of-the-breast-1 Accessed on January, 29 2016
- ↑ Lee M, Soltanian HT (2015). "Breast fibroadenomas in adolescents: current perspectives". Adolesc Health Med Ther. 6: 159–63. doi:10.2147/AHMT.S55833. PMC 4562655. PMID 26366109.
- ↑ Cerrato F, Labow BI (February 2013). "Diagnosis and management of fibroadenomas in the adolescent breast". Semin Plast Surg. 27 (1): 23–5. doi:10.1055/s-0033-1343992. PMC 3706050. PMID 24872735.