Pleomorphic adenoma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Pleomorphic adenoma was first described by Minssen in 1874 in a monograph named Ahlbom's. Later Mark and Dahlenfors in 1986 and Bullerdiek et al. in 1987 found some clonal chromosome abnormalities that are related to pleomorphic adenoma.

Historical Perspective

Discovery

In 1874, Minssen was the first to describe in detail about pleomorphic adenoma in monograph named Ahlbom's.^[1]
Later Mark and Dahlenfors in 1986 and Bullerdiek et al. in 1987 found some clonal chromosome abnormalities related to pleomorphic adenoma, with a majority them involving 8q12.^[2]
In 1987 Bullerdiek et al found another subset of tumors characterized by changes affecting 12q13-q15.^[3]

Landmark Events in the Development of Treatment Strategies

Impact on Cultural History

Famous Cases

The following are a few famous cases of [disease name]:

References

↑ Ghosh, Swapan Kr.; Saha, Jayanta; Chandra, Sudipta; Datta, Saumyajit (2011). "Pleomorphic Adenoma of the Base of the Tongue––A Case Report". Indian Journal of Otolaryngology and Head & Neck Surgery. 63 (S1): 113–114. doi:10.1007/s12070-011-0136-7. ISSN 2231-3796.
↑ Bullerdiek J, Raabe G, Bartnitzke S, Böschen C, Schloot W (June 1987). "Structural rearrangements of chromosome Nr 8 involving 8q12--a primary event in pleomorphic ademona of the parotid gland". Genetica. 72 (2): 85–92. PMID 3505884.
↑ Bullerdiek J, Bartnitzke S, Weinberg M, Chilla R, Haubrich J, Schloot W (1987). "Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)". Cytogenet. Cell Genet. 45 (3–4): 187–90. doi:10.1159/000132452. PMID 3691185.

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[GhoshSaha2011-1] Ghosh, Swapan Kr.; Saha, Jayanta; Chandra, Sudipta; Datta, Saumyajit (2011). "Pleomorphic Adenoma of the Base of the Tongue––A Case Report". Indian Journal of Otolaryngology and Head & Neck Surgery. 63 (S1): 113–114. doi:10.1007/s12070-011-0136-7. ISSN 2231-3796.

[pmid3505884-2] Bullerdiek J, Raabe G, Bartnitzke S, Böschen C, Schloot W (June 1987). "Structural rearrangements of chromosome Nr 8 involving 8q12--a primary event in pleomorphic ademona of the parotid gland". Genetica. 72 (2): 85–92. PMID 3505884.

[pmid3691185-3] Bullerdiek J, Bartnitzke S, Weinberg M, Chilla R, Haubrich J, Schloot W (1987). "Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)". Cytogenet. Cell Genet. 45 (3–4): 187–90. doi:10.1159/000132452. PMID 3691185.

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