Merkel cell cancer surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
The predominant therapy for Merkel cell cancer is surgical resection.
Surgery
- The initial standard approach for patients with merkel cell cancer is wide excision.
- According to:[1]
- European Dermatology Forum (EDF)
- European Association of Dermato-Oncology (EADO)
- European Organization of Research and Treatment of Cancer (EORTC) the primary tumour should be excised a margin of at least 1 to 2 cm of healthy tissue surrounding it is recommended.
- Overall survival rate in patients with merkel cell cancer increases dramatically by achieving negative margins during excision of the tumour.[2]
- Regional lymph nodes are often resection because they may contain cancer cells.
References
- ↑ Lebbe C, Becker JC, Grob JJ, Malvehy J, Del Marmol V, Pehamberger H, Peris K, Saiag P, Middleton MR, Bastholt L, Testori A, Stratigos A, Garbe C (November 2015). "Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline". Eur. J. Cancer. 51 (16): 2396–403. doi:10.1016/j.ejca.2015.06.131. PMID 26257075.
- ↑ Tai PT, Yu E, Tonita J, Gilchrist J (October 2000). "Merkel cell carcinoma of the skin". J Cutan Med Surg. 4 (4): 186–95. doi:10.1177/120347540000400403. PMID 11231196.