| Diseases
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Clinical manifestations
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Para-clinical findings
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Gold standard
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Additional findings
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| Symptoms
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Physical examination
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| Lab Findings
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Imaging
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Histopathology
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| Symptom 1
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Symptom 2
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Symptom 3
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Physical exam 1
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Physical exam 2
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Physical exam 3
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Lab 1
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Lab 2
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Lab 3
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Imaging 1
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Imaging 2
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Imaging 3
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| Cutaneous squamous cell carcinoma
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pain
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erythema
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indurated
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hyperkeratotic
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increased size
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skin biopsy
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- 60 percent of squamous cell carcinomas occur at the site of a previous actinic keratosis
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| Merkel cell carcinoma
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Starts on areas of skin exposed to the sun
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Single pink, red, or purple shiny bump
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Painless
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Skin biopsy
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blue-red, dome-shaped nodule
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| Nodular malignant melanoma
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- Two-thirds arise in normal skin, the rest in existing moles
- Genetic component in some cases with a positive family history
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| Amelanotic melanoma
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Color usually pink, purple or normal skin color
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Usually have an asymmetrical shape with an irregular border
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red, nonspecific lesion with slightly elevated borders
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skin biopsy
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- Do not make melanin, so lesions are not pigmented
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| Basal cell carcinoma
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Coarse scale lesion
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| Superficial basal cell carcinoma
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scaly patch
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erythematous lesion
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- large, hyperchromatic, oval nuclei and little cytoplasm
- well differentiated and cells appear histologically similar to basal cells of the epidermis
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skin biopsy
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| Nodular basal cell carcinoma
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Pearly papule with telangiectasias
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Skin biopsy
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| Cutaneous metastases of internal malignancy
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| Benign Skin Lesions
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| Sebaceous cell carcinoma
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| rhabdomyosarcoma
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| Actinic keratoses
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pain
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hyperkeratosis
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erythema
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less pigmentation, and tend to be somewhat smaller in size.
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Skin biopsy
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| Prurigo nodules
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Hard lesion
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Itchy lumps
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| Paget disease
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| Inflamed seborrheic keratosis
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waxy, "stuck on," often hyperkeratotic appearance
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On dermatoscopic evaluation, presence of horned cysts and hairpin-shaped blood vessels
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Skin biopsy
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| Viral warts
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Verrucous lesion
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Caused by HPV
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| Pyogenic granuloma
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Rapidly growing
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Red, dome-shaped
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Friable papule with a collarette of scale
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| Bowenoid papulosis
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multiple, red- to brown-colored, small papules that
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- primarily arise on genitals
- induced by human papillomavirus (HPV) infection
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| Nummular eczema
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Itchy lesions
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Coin shaped spots
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Chronic condition
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| Psoriasis
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| Pyoderma gangrenosum
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Purulent ulcer
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Ragged and violaceous border
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| Venous stasis ulcers
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| Traumatic ulcers
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| Bowen Disease
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| Sebaceous Hyperplasia
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| Trichoepithelioma
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| Allergic Contact Dermatitis
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| Atopic Dermatitis
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| Atypical Fibroxanthoma
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Erythematous, dome-shaped papule
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| Nevus
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| Chemical Burns
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| Limbal Dermoid
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| Benign hereditary intraepithelial dyskeratosis
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| primary acquired melanosis
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| fibrous xanthoma
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| Inflamed seborrheic keratosis
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Inflamed and hyperpigmented
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| Juvenile xanthogranuloma
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