Cancer of unknown primary origin differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Epidemiology and Demographics
Incidence
- The prevalence of cancer of unknown primary origin is approximately 10 cases per 100,000 individuals worldwide.[1][2]
- Cancer of unknown primary origin is common, and it accounts for 3–5% of all malignant epithelial tumors.[3]
- Cancer of unknown primary origin is the fourth most common cause of cancer-related death.[1]
Age
- Patients of all age groups may develop cancer of unknown primary origin.
- Cancer of unknown primary origin is more commonly observed among adults and elderly patients with a mean age of 59 upon presentation.[4]
Gender
- Cancer of unknown primary origin affects men and women equally except for squamous cell carcinomas where males are affected twice as frequently as females.[5]
Race
- There is no racial predilection to cancer of unknown primary origin.
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
References
- ↑ 1.0 1.1 Urban D, Rao A, Bressel M, Lawrence YR, Mileshkin L (2013). "Cancer of unknown primary: a population-based analysis of temporal change and socioeconomic disparities". Br. J. Cancer. 109 (5): 1318–24. doi:10.1038/bjc.2013.386. PMC 3778275. PMID 23860528.
- ↑ Fong T, Govindan R, Morgensztern D. Cancer of unknown primary. J Clin Oncol 2008 ASCO Ann Meet Proc. 2008;26 (15S:22159.
- ↑ Pavlidis N, Pentheroudakis G (2012). "Cancer of unknown primary site". Lancet. 379 (9824): 1428–35. doi:10.1016/S0140-6736(11)61178-1. PMID 22414598.
- ↑ Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P (1994). "Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients". J Clin Oncol. 12 (6): 1272–80. doi:10.1200/JCO.1994.12.6.1272. PMID 8201389.
- ↑ Muir C (1995). "Cancer of unknown primary site". Cancer. 75 (1 Suppl): 353–6. PMID 8001006.